题  目：Multimodal Neuroimaging of Sleep Deprivation and Fatigue

主讲人：饶恒毅教授（上海外国语大学脑与认知科学应用实验室）

时  间：2018年3月27日（星期二）上午10：00-11：00

地  点：心理学院214室

个人简介：

饶恒毅博士,教授，博士生导师，上海外国语大学脑与认知科学应用实验室执行主任，上海市特聘教授（东方学者），美国宾夕法尼亚大学助理教授。一直致力于发展和应用各种无创性脑成像技术来评测人脑的正常和异常工作状态，探讨人类行为的神经基础。研究领域包括认知神经科学、脑功能成像、神经管理学、神经语言学等交叉科学方向。研究课题曾获美国NIH和中国国家自然科学基金等多项资助，研究经费近千万美元。已经在Science, PNAS, NeuroImage等国内外学术期刊和国际会议上发表了近200篇学术论文和会议报告，被世界各国学者引用超过4000次，研究成果被CNN, US NEWS, Science Daily等国际媒体多次报导，受邀担任多个国际SCI期刊编委和数十种SCI/SSCI期刊审稿人，以及美国，加拿大，英国，中国香港等多个国家和地区基金项目评审专家。

讲座内容：

Human typically spends around one-third of their lives sleeping. Obtaining sufficient sleep is essential for optimal brain and behavioral functioning. However, millions of people, including many students, frequently reduce their sleep time due to work demands, leisure time, and family obligations. Sleep loss has been shown to increase fatigue and sleep propensity, reduce alertness and vigilance, slow psychomotor and cognitive speed, promote wake state instability, and cause considerable social, financial and health-related costs. A recent evidence-based consensus recommendation for the amount of sleep needed to promote optimal health in adults concluded that sleeping less than 7 hours/night (especially ≤6h) was associated with impaired performance, greater risk of accidents, and adverse health outcomes, including obesity, diabetes, hypertension, heart disease, stroke, depression, impaired immune function, increased pain, and risk of death. Although the negative effects of sleep loss on human behavior have been studied for more than a century, how sleep deprivation impairs human brain remains unclear. Here we used multimodal neuroimaging approach to examine the detrimental effects of sleep deprivation on human brain activity and connectivity as well as the relationships between brain deficits, fatigue, and other behavior dysfunction after sleep loss.