摘要：The term “conduct problems” refers to a pattern of repetitive rule-breaking behavior, aggression, and disregard for others. Such problems have received increased attention recently, owing to violent events perpetrated by youth. Empirical evidence suggests that mental processes that related to inhibition control and capacity of empathy is disrupted among these adolescents, but the neural substrate of these observations is far from clarification. Recent findings additionally revealed that genetics that driving neural plasticity and regulating neural activity may participant in these processes, adding the complexity of elucidating the exact mechanism of this disturbing condition. In this talk, I will present current findings by integrating cognitive, neuroimaging and genetic perspectives.